Wednesday, January 8, 2020

Meaning of capsules.
Capsules

Capsules are the solid unit dosage from of medicament in
which the drugs are enclosed in a practically tasteless, hard
or  soft soluble container or shell made up of a suitable

form of gelatin. Hard capsules are used for filling the solid
substances. Hard gelatin capsules are available in a number
of sizes which varies from 000 to 5, the former being the
largest and latter the smallest. They are made up of two
cylindrical halves, one slightly larger in diameter but shorter
in length known as cap and the other slightly shorter in diameter
but longer in length know as base. the medicament is filled in
longer narrower half, then the cap is fitted over the open end
available in a number
two
by moistening edges of the lower half of the capsule.
Soft capsules are flexible in nature. They may be spherical.
ovoid, cylindrical or tubes. The spherical capsules are also
known as Pearls'. Soft gelatin capsules are used for enclosing
the solids, liquids and semi-liquids.
Enteric coated capsules are the capsules which are treated
or coated in such a way that the capsule does not disintegrate
in the acidic medium of the stomach but disintegrate in the
alkaline medium of the small intestine. Enteric coated capsules
have been largely replaced by enteric coated tablets.
Capsules are increasing their popularity day by day. Hard
capsule comes second to tablets in importance as solid unit
dosage forms. Some of the capsules are administered through
rectum and vagina and are convenient mode of administration
of drugs than suppositories. For oral administration the capsule
is placed on the tongue and swallowed with a drink of water.

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